The Doctor
Dr Kalomoira Kefala, Paediatric Allergist
A dual expertise in paediatrics and allergology, built over more than 15 years in hospital settings and dedicated to the most complex cases.
The Doctor
About Dr Kefala
Since 2017, I have been practising in Paris as a paediatric allergist.
I provide the exploration, treatment and follow-up of allergic and respiratory conditions in infants, children and adolescents.
I manage the full range of allergic conditions in children, exploring both respiratory and food allergies. I also practise allergen immunotherapy (desensitization) for children with multiple allergies.
I founded the Paediatric and Adolescent Allergy Clinic in Paris, where I draw on my clinical and research experience to help allergic patients and ease the burden of their allergies.
Training & Research
I hold a Master of Science in Medical Research Methodology, worth 120 European credits.
My doctoral thesis focused on the tuberculin index in children.
I subsequently specialised in Paediatric Pulmonology and Allergology, training in Belgium, France and England.
I hold a HERMES diploma in spirometry from the European Respiratory Society (ERS) — a two-year programme with final examinations in Germany.
The causes and treatment of respiratory distress, as well as allergies in infants and children, are my main areas of scientific interest. I have publications across numerous fields related to Immunology and Allergy, as well as Respiratory and Sleep Medicine (Infectious Diseases, Haematology-Immunology, Paediatric Dermatology, Respiratory and Sleep Medicine, and Neonatal Intensive Care).
I regularly present my work at the congresses of the European Academy of Allergy and Clinical Immunology (EAACI), the European Respiratory Society (ERS), and the European and World Sleep Societies (eSleep and World Sleep Society).
Published Books
I have published numerous books for patients living with allergies ("Doctor, Why Am I Allergic?"), translated into many languages. Clinical research — internal and observational (cohort-based), grounded in the follow-up of my own patients — has become part of my daily work, and I have progressively integrated it into my practice to improve care.
Work on Eczema and Contact Allergies
My work with patients suffering from eczema helped me effectively identify a child with an antiseptic allergy presenting facial oedema, as well as children reacting to excipients in antiseptics and cosmetics. This work has been published in the Revue Française d'Allergologie, with a further part published in the international journal Pediatric Dermatology.
Neonatal Intensive Care and Neonatology
I worked for many years in a neonatal intensive care unit. As a result, I have experience treating severe respiratory distress and applying non-invasive ventilation, and I hold a sub-specialisation in neonatology.
My training in paediatric allergology-pulmonology and my work in intensive care, treating children with respiratory distress and sometimes congenital malformations, allowed me to deepen my knowledge of respiratory distress and the use of ventilation modes in children. My training in immunology-haematology and infectious diseases broadened my knowledge of paediatric allergology.
Early Prevention of Allergies and Comorbidities
I aim to identify allergies and asthma early, to halt their progression and prevent the onset of comorbidities such as obesity and attention/hyperactivity neurodevelopmental disorders.
In this context, I have worked to distinguish obstructive-type sleep apnoea-hypopnoea syndrome (OSAHS) in children from non-obstructive OSAHS.
Sleep Disorders in the Allergic Child
I have completed several international training programmes on sleep apnoea and regularly attend courses run by the European Respiratory Society and the European and World Sleep Societies.
I presented two patients who were successfully diagnosed and treated in the e-learning programme of the European Respiratory Society.
In parallel, I have presented and published on the specific characteristics of allergic children with sleep apnoea, who show a distinct profile from children with obstructive-type OSAHS, as well as the link with asthma and obesity. This work has helped treat allergic children early and prevent the progression of inflammatory diseases.
I have studied and published on the role of increased respiratory effort during sleep in relation to allergies, asthma and obesity. Measuring respiratory effort at night helps improve children's sleep on a day-to-day basis.
In this context, I perform outpatient polygraphy and polysomnography to accurately identify the profile of children with sleep disorders, in order to treat and refer them appropriately.
A Comprehensive, Personalised Approach
My broad-ranging knowledge and experience help me treat allergic children while taking full account of their comorbidities and associated medical conditions, such as obesity and ADHD.
I have experience in parenteral nutrition and in the care of infants with severe oral disorders requiring specific nutritional needs, as well as in facilitating their oral feeding.
I place particular importance on personalised treatment. I am equally mindful of the role that exposure to certain factors plays in the development of allergies, asthma and inflammatory diseases.
Training
Degrees & Certifications
A comprehensive academic background in medicine, paediatrics and allergology, complemented by regular continuing education.
State Diploma of Doctor of Medicine
A complete medical education, forming the foundation of her entire clinical practice.
Specialised Studies Diploma (DES) in Paediatrics
Hospital-based specialisation dedicated to child and adolescent health.
University Diploma (DU) in Allergology and Clinical Immunology
In-depth study of allergic and immunological mechanisms in children.
Additional Training in Children's Sleep Disorders
Paediatric respiratory polygraphy and polysomnography.
Member of International Scientific Societies
European Academy of Allergy and Clinical Immunology (EAACI) (member since 2014), ERS — European Respiratory Society (member since 2013), ESRS (European Sleep Research Society), WSS (World Sleep Society) and FENS (Federation of European Neuroscience Societies) — continuing education and international scientific monitoring.
Sub-Specialisation in Neonatal Intensive Care
Experience gained in a neonatal intensive care unit: severe respiratory distress, non-invasive ventilation and care of fragile newborns.
Master of Science in Medical Research Methodology
Awarded with 'Excellent' honours by Aristotle University of Thessaloniki (120 ECTS credits, 4 semesters), with a thesis on the tuberculin index in children.
Member of National Scientific Societies and a Professional Union
Member of SFA — Société Française d'Allergologie (since 2019), as well as SFRMS, CIAB, Paris Allergie, Anaforcal, AFPA, SFECHO and SPLF (Société de Pneumologie de Langue Française), and member of the SYFAL professional union.
Degrees & Certificates
Complementary Practice Certificate in Allergology
Intensive Care Specialisation Certificate
University Certificate (CU) in Clinical Immuno-Allergology — ULB (official translation)
State Diploma of Doctor of Medicine
Specialised Studies Diploma (DES) in Paediatrics
European Equivalence of the Paediatrics Diploma
ERS HERMES Certificate — European Spirometry Driving Licence (Part 1)
ERS HERMES Certificate — European Spirometry Driving Licence (Part 2)
Certificate in Clinical Immuno-Allergology — ULB
Master of Science — Methodology of Medical Research (detailed course and grade transcript, English)
Allergy Diploma — University of Southampton (1/4)
Allergy Diploma — University of Southampton (2/4)
Allergy Diploma — University of Southampton (3/4)
Allergy Diploma — University of Southampton (4/4)
Master of Science — Methodology of Medical Research (official diploma translation, French)
University Certificate in Spirometry — University of Liège (Belgium)
University Certificate in Paediatric Airway Management — University of Liège (Belgium)
University Certificate in Paediatric Airway Management — Annex (training details)
Photo — Honour board of the spirometry programme laureates, ERS Congress 2016 (London)
Allergy Diploma — University of Southampton, Diploma Supplement (1/2)
Allergy Diploma — University of Southampton, Diploma Supplement (2/2)
Recognition
Award & Distinction
Scientific commitment recognised by Europe's leading authorities in allergology.
EAACI Distinction
Awarded by the European Academy of Allergy and Clinical Immunology (EAACI) for her work on complex allergic cases.
Recognition of Clinical Research
Work distinguished for its contribution to understanding the links between allergies and sleep disorders.
Speaker
Regularly presents her work at international congresses.
Best Poster Presentation Award
I am honoured to receive an award for the abstract I presented at the 2026 congress of the European Academy of Allergy and Clinical Immunology (EAACI), held in Istanbul from 12 to 15 June!
I am delighted that the work I have initiated and carried out over the years, in response to my patients' needs, is resonating with respected researchers and clinicians.
I hope this work will pave the way for a better definition of the disease and for appropriate nutrition, enabling early treatment and effective prevention.
A heartfelt thank you to all the patients who took part in the study; they are the ones who benefited first and foremost. I have done everything I can to make sure their voice was heard.
A huge thank you to the European Academy of Allergy and Clinical Immunology (EAACI) for this recognition and for organising such an inspiring event.
Congratulations to all the other presenters and award winners!
View the certificate →Scientific Outreach
European Congresses & Scientific Topics
An active presence at major scientific events in allergology and paediatric pulmonology across Europe.
EAACI Congress (European Academy of Allergy and Clinical Immunology)
Participation in annual congresses dedicated to advances in paediatric allergology.
Scientific Topics Presented
Sublingual desensitization in children, paediatric asthma phenotypes, and the link between allergic background and sleep-related breathing disorders.
Screening for Infection Latent Tuberculosis — Update 2013
Leuven (Belgium), 10 March 2013.
European Meeting of Paediatric Allergy and Asthma — EAACI PAAM 2013
17-19 October 2013, Athens, Greece.
Congress Certificates
Presentations
Presentations at European Congresses
A selection of Dr Kefala's talks and scientific communications at European congresses in allergology and paediatric pulmonology.
"Sublingual Desensitization in Children: A Practical Approach"
Annual EAACI Congress — oral presentation on paediatric sublingual immunotherapy protocols.
"Paediatric Asthma Phenotypes and Allergic Background"
European Congress of Paediatric Pulmonology — presentation of a clinical case series.
"Sleep Disorders and Respiratory Allergies in Children"
European Clinical Research Seminar — practical experience and clinical data.
Presentations and posters
EAACI 2022 — Microarousals and Asthma
EAACI 2022 — Microarousals and Dust Mites
EAACI 2022 — Severe OSA and Eczema
EAACI 2022 — Severe Sleep Disorders and Alternaria
EAACI 2023 — Increased RE, Alternaria and Rhinitis
EAACI 2024 — Increased RE, SEIPA, Metabolic Disorders, OSA and Stress
EAACI 2024 — Late Reaction to Wheat and Butter, Stress
EAACI 2025 — Oxidative Stress
FENS 2025 (Crete) — Increased RE and Autism
EAACI 2026 (Istanbul) — Outstanding Poster Presentation Award: Polysorbate 80 (E433) sensitisation, chronic cough and ODB
Scientific Background
International Communications
An overview of oral and poster presentations delivered between 2006 and 2021 at international congresses in paediatrics, haematology-immunology, pulmonology and allergology.
International Congresses (2006-2013)
Pearson's Syndrome in an infant heterozygous also for C282Y allele of HFE gene
11th European Hematology Association Congress, 15-18 June 2006, Amsterdam — poster. K. Kefala-Agoropoulou, E. Roilides, A. Lazaridou, E. Farmaki, Savopoulou, H. Tsantali, J.N. Tsiouris.
Cutaneous zygomycosis in an infant with Pearson's syndrome
European Congress of Infectious Diseases ISHAM, Paris, 25-28 June 2006 — poster. K. Kefala-Agoropoulou, E. Farmaki, A. Velegraki, J.N. Tsiouris, E. Roilides.
Community-Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA) Severe Infection in Children: Case Report and Review of Published Cases
International Congress of Paediatrics 2007, 25-30 August, Athens — poster (PPO586). Kalomoira Kefala-Agoropoulou, Sofia Sarafidou, Konstantinos Kollios, Athanasia Anastasiou, Danai Sofianou, Emmanuel Roilides.
Simultaneous Kawasaki Disease in Siblings with Uncommon Complications and Review of the Literature
International Congress of Paediatrics 2007, 25-30 August, Athens — poster (PP1074). Kalomoira Kefala-Agoropoulou, Agathi Karagiannidou, Andrianna Mpounta, Markella Lioliou, Emmanuel Roilides, Theodouli Papastavrou.
Non-Epidemic E.coli O157:H7-Associated Haemolytic Uraemic Syndrome: 3 Cases During One Year in Northern Greece
International Congress of Paediatrics 2007, 25-30 August, Athens — poster (PP0783). Konstantinos Kollios, Kefala-Agoropoulou Kalomoira, Antonios Platnaris, Emmanuel Roilides, Nikoleta Printza, Maria Badouraki, Theodouli Papastavrou, A. Kansouzidou-Kanakoudi.
Neonatal Alloimmune Thrombocytopenia
Congress of the European Society of Paediatric Hematology and Immunology (ESPHI), 5-8 November 2009 — oral presentation. Kefala-Agoropoulou Kalomoira, Soubassi Vassiliki, Evdoridou Ioanna, Zoulas Dimitrios, Sarafidis Kosmas, Agakidou Eleni, Drossou Vassiliki.
A case of congenital histiocytosis: Difficulties in differential diagnosis and discrimination between different types
Congress of ESPHI, 5-8 November 2009 — poster. Kalomoira Kefala-Agoropoulou, Maria Pantikidou, Olympia Lekidou, Elissavet Diamanti, Ioannis Tsiouris.
Late Onset Neutropenia in VLBW Neonates
15th European Hematology Association Congress, 10-13 June 2010, Barcelona — poster (P265). Kefala-Agoropoulou Kalomoira, Evdoridou Ioanna, Papakyriakidou Panagiota, Tsepketzi Eleni, Agakidou Eleni, Drossou Vassiliki.
Thrombocytopenia and platelet indices in septic neonates
15th European Hematology Association Congress, 10-13 June 2010, Barcelona — poster (P196). Kefala-Agoropoulou Kalomoira, Evdoridou Ioanna, Sarafidis Kosmas, Elissavet Diamanti, Soubassi Vassiliki, Drossou Vassiliki.
Decrease of tuberculin index in children of Central Macedonia, Greece
31st Congress of the European Society for Paediatric Infectious Diseases (ESPID), 28 May - 2 June, Milan, Italy — poster. K. Kefala-Agoropoulou, E. Chatzigianni, C. Antachopoulos, E. Iosifidis, E. Roilides.
European Respiratory Society Congresses (2015-2021)
High-flow nasal cannula heated-humidified (HFNC) oxygen versus low-flow oxygen in infants with bronchiolitis needing oxygen administration: preliminary results
ERS Congress, Amsterdam, September 2015. Kalomoira Kefala, Kindja Nyamugabo, Nesrine Farhat, Aurélie Janssen, Marie-Christine Seghaye (CHU NDB Liège).
High flow nasal cannula (HFNC) long term benefits through a study exploring links between bronchiolitis and (epigenetic) influence of virus to asthma evolution
ERS International Congress, London, 6 September 2016. K. Kefala, M-Ch. Seghaye.
Links between exercise-induced asthma and allergies in children: Should we pay a little more attention to children who are breathless to the effort?
ERS International Congress, London, 7 September 2016. K. Kefala, C. Hebette, C. Castigliano, M. Fonteyn, J. Harvengt, M-Ch. Seghaye.
The role of allergies and tobacco exposure in Obstructive Sleep Apnea Syndrome Type I/II in children, and Sublingual Immunotherapy for children with OSAS I/II with an Allergic Profile
E-poster — ERS/ESRS Sleep & Breathing Conference 2021. Kalomoira Kefala.
Persistently increased respiratory effort during sleep in children with obstructive sleep apnea is indicative of allergy/asthma, obesity risk and inadequate treatment
ERS Congress (Virtual), 5-8 September 2021. Kalomoira Kefala, François Lavaud, Agnès Linglart, Philippe Guérin. DOI: 10.1183/13993003.congress-2021.PA3083.
Scientific Activity
Reviewer for International Journals
Contributing to the peer review of scientific articles submitted to international journals.
Reviewer for Scientific Reports (Springer Nature)
Contributed to the review of scientific manuscripts for the journal Scientific Reports in 2024 and 2025.
Reviewer for BMC Pulmonary Medicine (Springer Nature)
Reviewed a manuscript on the early prediction of ventilator-associated pneumonia in critical care patients.
Reviewer Certificates
Commitment
Volunteering
A community-driven, charitable commitment to children and families.
Free Screening Day — World Allergy Week
Organisation of a free allergy screening day to mark World Allergy Week.
Our Approach
Letting Children Speak
A listening-centred approach that places the child's own words at the heart of the consultation, alongside the discussion with parents.
Before being a patient, the child is the first witness to what they are feeling: letting them speak is often the shortest path to the right diagnosis.
Mentoring
Supporting Student Trainees
A pedagogical welcome for secondary-school students on work-experience placements, alongside the clinic's regular activity.
Troisième Work-Experience Placement
Support for secondary-school students hosted during their troisième (final year of lower-secondary school) work-experience placement, notably in preparing their placement report and, depending on the school, their oral presentation. These students went on to pass their brevet diploma through their own efforts.